Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009242 | 0.96 | MEN1 (0.57) | MEN1KMT2AHTR2AKCNH2SLC6A2 | |
| SCHEMBL6007356 | 0.89 | HTR2A (0.61) | MEN1KMT2AHTR2AKCNH2SLC6A2 | |
| SCHEMBL3838690 | 0.85 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL6009245 | 0.85 | MGLL (0.54) | MEN1KMT2AHTR2AKCNH2 | |
| SCHEMBL3838692 | 0.85 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL3838687 | 0.85 | HTR2A (0.61) | HTR2ASLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL6007996 | 0.85 | MEN1 (0.55) | MEN1KMT2AHTR2AKCNH2SLC6A2 | |
| SCHEMBL6007922 | 0.85 | SLC18A3 (0.57) | MEN1KMT2AHTR2AKCNH2 | |
| SCHEMBL6007909 | 0.81 | MGLL (0.54) | MEN1KMT2AHTR2AKCNH2 | |
| SCHEMBL6007910 | 0.80 | KCNH2 (0.50) | HTR2AKCNH2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |