⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77400 | 0.93 | DGKA (0.68) | — | |
| SCHEMBL26108905 | 0.91 | DGKA (0.72) | — | |
| SCHEMBL78129 | 0.84 | — | — | |
| SCHEMBL10099629 | 0.84 | DGKA (0.62) | — | |
| SCHEMBL8680864 | 0.83 | — | — | |
| SCHEMBL127083 | 0.82 | — | — | |
| Ethylene Glycol Dipentanoate SCHEMBL812973 | 0.82 | DGKA (0.82) | — | |
| SCHEMBL807414 | 0.81 | DGKA (0.54) | — | |
| SCHEMBL2532239 | 0.81 | DGKA (0.65) | — | |
| SCHEMBL30950609 | 0.81 | CYP1A2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | claimed |
| WO-1997048444-A1 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | BECTON DICKINSON AND COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | claimed |
| EP-2497475-A1 | Treatment of laminitis with platelet aggregation inhibitors | Dussler, Sabine (DE) | 2012-09-12 | — | — | EP | disclosed |
| EP-0920345-A4 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | VYTERIS INC (US) | 2006-05-10 | — | — | EP | disclosed |
| EP-0761672-B1 | Cephalosporins containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments | AVENTIS PHARMA SA (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| EP-0920345-A1 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | Becton Dickinson and Company (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| EP-0693496-A1 | Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1996-01-24 | — | — | EP | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |
| US-5436242-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0628562-A1 | Cephalospornis having in position 7 as substituted axymino radical, intermediates, processes for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1994-12-14 | — | — | EP | disclosed |
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0542411-A2 | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |