Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948948 | 1.00 | SIGMAR1 (0.54) | SIGMAR1POLBALDH1A1LMNASLC6A2 | |
| SCHEMBL23496876 | 1.00 | SIGMAR1 (0.54) | SIGMAR1POLBALDH1A1LMNASLC6A2 | |
| SCHEMBL1738860 | 0.88 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3CA1 | |
| SCHEMBL8101234 | 0.88 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3CA1 | |
| SCHEMBL2080509 | 0.88 | SIGMAR1 (0.53) | SIGMAR1SLC6A2SLC6A4SLC6A3CA1 | |
| SCHEMBL22640155 | 0.86 | ALDH1A1 (0.52) | SIGMAR1POLBALDH1A1GAAMEN1 | |
| SCHEMBL22640117 | 0.86 | ALDH1A1 (0.52) | SIGMAR1POLBALDH1A1GAAMEN1 | |
| SCHEMBL6323998 | 0.84 | SLC6A2 (0.50) | SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1415727 | 0.83 | SLC6A2 (0.63) | SIGMAR1SLC6A2SLC6A4SLC6A3CA1 | |
| SCHEMBL6936570 | 0.83 | SLC6A2 (0.63) | SIGMAR1SLC6A2SLC6A4SLC6A3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051410-A1 | AZABENZOXAZOLES FOR THE TREATMENT OF CNS DISORDERS | PFIZER INC. (US) | 2006-05-18 | — | — | WO | disclosed |