Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189619 | 0.88 | SIGMAR1 (0.47) | SIGMAR1TDP1CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL26893117 | 0.82 | SIGMAR1 (0.47) | SIGMAR1TDP1CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL19486854 | 0.82 | SIGMAR1 (0.47) | SIGMAR1TDP1CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL9842011 | 0.80 | TDP1 (0.42) | SIGMAR1TDP1CYP2C19 | |
| SCHEMBL4996661 | 0.78 | — | — | |
| SCHEMBL10991627 | 0.78 | RAB9A (0.39) | — | |
| SCHEMBL6964856 | 0.78 | ALDH1A1 (0.45) | — | |
| SCHEMBL3631849 | 0.78 | SIGMAR1 (0.40) | SIGMAR1TDP1CYP2C19 | |
| SCHEMBL6891286 | 0.78 | SLC6A4 (0.41) | SIGMAR1TDP1CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL9842021 | 0.77 | TDP1 (0.42) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051410-A1 | AZABENZOXAZOLES FOR THE TREATMENT OF CNS DISORDERS | PFIZER INC. (US) | 2006-05-18 | — | — | WO | disclosed |