SCHEMBL6008671

SCHEMBL6008671

CC(C)(C)OC(=O)NC(CBr)Cc1cccc(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.60
ATM Q13315 1/20 0.52
CTSS P25774 5/20 0.47
CTSK P43235 4/20 0.47
CTSB P07858 3/20 0.47
APP P05067 3/20 0.43
ACE P12821 1/20 0.43
KDM4E B2RXH2 1/20 0.43
AAK1 Q2M2I8 1/20 0.43
CYP3A4 P08684 1/20 0.42
SCN9A Q15858 1/20 0.42
SYK P43405 1/20 0.41
PNMT P11086 1/20 0.41
FFAR2 O15552 1/20 0.40
KLK5 Q9Y337 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13905628 0.89 CTSL (0.61) CTSLATMCTSSCTSKCTSB
SCHEMBL742227 0.87 CTSL (0.62) CTSLATMCTSSCTSKCTSB
SCHEMBL742226 0.87 CTSL (0.62) CTSLATMCTSSCTSKCTSB
SCHEMBL14282774 0.87 CTSL (0.59) CTSLATMCTSSCTSKCTSB
SCHEMBL1519856 0.87 CTSL (0.62) CTSLATMCTSSCTSKCTSB
SCHEMBL5757441 0.85 ATM (0.53) CTSLATMCTSSCTSKCTSB
SCHEMBL5755877 0.84 ATM (0.70) CTSLATMCTSSCTSKCTSB
SCHEMBL8330079 0.84 ATM (0.70) CTSLATMCTSSCTSKCTSB
SCHEMBL5757675 0.84 ATM (0.47) CTSLATMCTSSCTSKCTSB
SCHEMBL21799327 0.84 CTSL (0.64) CTSLATMCTSSCTSKCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SK BIOPHARMACEUTICALS CO., LTD. (KR) 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SIGMAR1, TAAR1, OPRL1 CTSL 4664/4885ATM 3190/4885CTSS 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.