Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008834 | 0.88 | SIGMAR1 (0.56) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL5755483 | 0.86 | MEN1 (0.50) | CCR3MEN1KMT2ASMN1; SMN2HTR1A | |
| SCHEMBL6007492 | 0.85 | SLC6A2 (0.48) | CCR3MEN1KMT2ASMN1; SMN2SLC6A2 | |
| SCHEMBL6007980 | 0.83 | CARM1 (0.52) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL6008656 | 0.83 | ALDH1A1 (0.47) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL6007453 | 0.83 | ALDH1A1 (0.49) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL6008203 | 0.79 | SIGMAR1 (0.50) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL6009428 | 0.78 | ALDH1A1 (0.53) | CCR3MEN1KMT2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6007421 | 0.77 | ALDH1A1 (0.52) | CCR3MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL4961538 | 0.76 | CCR3 (1.00) | CCR3MEN1KMT2ASMN1; SMN2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |