Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974672 | 0.82 | LMNA (0.37) | MCL1LMNA | |
| SCHEMBL1289911 | 0.79 | — | — | |
| SCHEMBL15775001 | 0.79 | FAAH (0.46) | LMNA | |
| SCHEMBL8654432 | 0.78 | — | — | |
| SCHEMBL16269487 | 0.75 | — | — | |
| SCHEMBL6309952 | 0.74 | MCL1 (0.40) | MCL1LMNA | |
| SCHEMBL5451540 | 0.72 | — | — | |
| SCHEMBL1297846 | 0.72 | — | — | |
| SCHEMBL410254 | 0.71 | — | — | |
| SCHEMBL487785 | 0.70 | LMNA (0.48) | MCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |