SCHEMBL6009005

SCHEMBL6009005

O=S(=O)(F)CCCCCF

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.59
MGLL Q99685 9/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28227209 1.00 FAAH (0.59) FAAHMGLL
SCHEMBL19421383 0.97
SCHEMBL12136466 0.88
SCHEMBL28473138 0.87 FAAH (0.72) FAAHMGLL
SCHEMBL1469615 0.84 FAAH (0.67) FAAHMGLL
SCHEMBL1470382 0.77 FAAH (0.58) FAAHMGLL
SCHEMBL9164829 0.77 FAAH (0.35) FAAH
SCHEMBL8608468 0.77 FAAH (0.59) FAAHMGLL
SCHEMBL14775349 0.75 CA2 (0.33) FAAH
SCHEMBL6908004 0.74 APP (0.55) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells E. I. DU PONT DE NEMOURS AND COMPANY 2006-08-10 US claimed
WO-2005003081-A2 SULFONIMIDE CONTAINING COMPOUNDS AND THEIR USE IN POLYMER ELECTROLYTE MEMBRANES FOR ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO claimed
CN-108137638-A Bridging type nucleic acid GuNA, its manufacturing method and midbody compound 田边三菱制药株式会社 2018-06-08 CN disclosed
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells E. I. DU PONT DE NEMOURS AND COMPANY 2006-08-10 US disclosed
WO-2005003081-A2 SULFONIMIDE CONTAINING COMPOUNDS AND THEIR USE IN POLYMER ELECTROLYTE MEMBRANES FOR ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells HCN2, KCNN2, NHERF1 FAAH 3941/4885MGLL 4672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.