Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268472 | 0.86 | KMT2A (0.60) | MEN1KMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL27735382 | 0.84 | MEN1 (0.58) | MEN1KMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL6009094 | 0.81 | KDM4E (0.55) | MEN1KMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL6009091 | 0.81 | KDM4E (0.55) | MEN1KMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL9311985 | 0.76 | KMT2A (0.75) | MEN1KMT2AALDH1A1HPGDP2RX7 | |
| SCHEMBL13901352 | 0.76 | KMT2A (0.55) | MEN1KMT2ANPSR1ALDH1A1HPGD | |
| SCHEMBL2049574 | 0.75 | HPGD (0.59) | ALDH1A1HPGDHTTCYP3A4CYP2C19 | |
| SCHEMBL29389982 | 0.75 | KMT2A (0.68) | MEN1KMT2AALDH1A1HPGDHTT | |
| SCHEMBL17434797 | 0.75 | KMT2A (0.68) | MEN1KMT2AALDH1A1HPGDHTT | |
| SCHEMBL5186995 | 0.75 | MEN1 (0.68) | MEN1KMT2AHPGDKCNQ2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MEN1 3791/4885KMT2A 1652/4885NPSR1 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.