Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009484 | 0.96 | CTSK (0.50) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL6007487 | 0.91 | CTSK (0.52) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL21714668 | 0.86 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL4714695 | 0.86 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL19348946 | 0.86 | MAPT (0.53) | CTSKCTSSMAPTATMHDAC4 | |
| SCHEMBL24876855 | 0.85 | CTSK (0.50) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL7325276 | 0.85 | CTSK (0.50) | CTSKCTSSMAPTATM | |
| SCHEMBL27477565 | 0.85 | CTSK (0.50) | CTSKCTSSMAPTATM | |
| SCHEMBL6007345 | 0.85 | CTSK (0.54) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL30638536 | 0.85 | CTSK (0.54) | CTSKCTSSMAPTGABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |
| US-20030105079-A1 | Novel phenylalkyl diamine and amide analogs | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105079-A1 | Novel phenylalkyl diamine and amide analogs | SIGMAR1, TAAR1, OPRL1 | CTSK 4744/4885CTSS 4613/4885MAPT 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.