SCHEMBL6007487

SCHEMBL6007487

CC(C)(C)OC(=O)NC(CCBr)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.52
CTSS P25774 4/20 0.52
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
AKT1 P31749 1/20 0.45
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRB2 P47870 1/20 0.44
PPARA Q07869 2/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009484 0.92 CTSK (0.50) CTSKCTSSMAPTATMAKT1
SCHEMBL6009263 0.91 CTSK (0.49) CTSKCTSSMAPTATMAKT1
SCHEMBL6007345 0.88 CTSK (0.54) CTSKCTSSMAPTATMAKT1
SCHEMBL30638536 0.88 CTSK (0.54) CTSKCTSSMAPTATMAKT1
SCHEMBL4583120 0.87 CTSK (0.53) CTSKCTSSMAPTATMCTSL
SCHEMBL56698 0.87 CTSK (0.53) CTSKCTSSMAPTATMCTSL
SCHEMBL4961187 0.87 CTSK (0.56) CTSKCTSSMAPTATMCTSL
SCHEMBL56596 0.87 CTSK (0.53) CTSKCTSSMAPTATMCTSL
SCHEMBL28464584 0.87 CTSK (0.53) CTSKCTSSMAPTATMCTSL
SCHEMBL4353938 0.87 CTSK (0.53) CTSKCTSSMAPTATMCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078537-B2 Phenylalkyl diamine and amide analogs SK CORPORATION (KR) 2006-07-18 US disclosed
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SK BIOPHARMACEUTICALS CO., LTD. (KR) 2003-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105079-A1 Novel phenylalkyl diamine and amide analogs SIGMAR1, TAAR1, OPRL1 CTSK 4744/4885CTSS 4613/4885MAPT 929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.