SCHEMBL6009469

SCHEMBL6009469

O=C(O)CCC(C(=O)O)N(C(=O)C(O)CO)C(=O)C(O)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.47
KDM4A O75164 2/20 0.47
KDM4C Q9H3R0 2/20 0.47
KDM2A Q9Y2K7 2/20 0.47
TET3 O43151 1/20 0.47
OR51E2 Q9H255 1/20 0.41
FOLH1 Q04609 6/20 0.39
GRM3 Q14832 3/20 0.36
CYP1A2 P05177 2/20 0.36
GRM8 O00222 1/20 0.36
GRM6 O15303 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GSR P00390 1/20 0.36
GRIK1 P39086 1/20 0.36
GRM5 P41594 1/20 0.36
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
SLC1A3 P43003 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010143 0.82 OR51E2 (0.50) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL6009855 0.79 OR51E2 (0.39) OR51E2GSR
SCHEMBL6009555 0.77 RNPEP (0.42) OR51E2FOLH1
SCHEMBL6010162 0.77 GSR (0.43) OR51E2FOLH1GSR
SCHEMBL28464434 0.76 GRM8 (0.44) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL30577766 0.76 TET2 (0.46) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL6009565 0.74 OR51E2 (0.41) OR51E2SLC1A3SLC1A2
SCHEMBL28666295 0.72 CYP1A2 (0.52) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL10523165 0.72 CYP1A2 (0.52) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL28486157 0.71 GRM8 (0.52) TET2KDM4AKDM4CKDM2ATET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA TET2 694/4885KDM4A 3850/4885KDM4C 4250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.