SCHEMBL6010143

SCHEMBL6010143

O=C(O)C(CO)N(C(=O)C(O)CO)C(=O)C(O)CO

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.35
TET2 Q6N021 6/20 0.32
TET3 O43151 2/20 0.32
TET1 Q8NFU7 1/20 0.32
PDE4A P27815 1/20 0.32
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30
GABRR1 P24046 2/20 0.30
KDM4A O75164 2/20 0.30
KDM4C Q9H3R0 2/20 0.30
KDM2A Q9Y2K7 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009469 0.82 TET2 (0.47) OR51E2SMN1; SMN2TET2TET3KDM4A
SCHEMBL6009565 0.82 OR51E2 (0.41) OR51E2
SCHEMBL6009855 0.79 OR51E2 (0.39) OR51E2GABRR1
SCHEMBL6010162 0.78 GSR (0.43) OR51E2
SCHEMBL6009555 0.78 RNPEP (0.42) OR51E2LMNA
SCHEMBL6009849 0.77 CYP1A2 (0.46)
SCHEMBL6010336 0.76 OR51E2 (0.48) OR51E2SMN1; SMN2PDE4A
SCHEMBL28220236 0.76 SLC1A1 (0.39) OR51E2USP2SLCO1B1
SCHEMBL6010225 0.75 OR51E2 (0.35) OR51E2
SCHEMBL6010256 0.74 SLC7A5 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA OR51E2 2335/4885SMN1; SMN2 3951/4885SLC22A6 2299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.