Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009499 | 0.85 | ALDH1A1 (0.62) | SLC9A1ALDH1A1HPGDTSHRS1PR4 | |
| SCHEMBL6009556 | 0.81 | SLC9A1 (0.56) | SLC9A1ALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL6010443 | 0.80 | SLC9A1 (0.52) | SLC9A1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL6009509 | 0.78 | SLC9A1 (0.56) | SLC9A1ALDH1A1HPGDADORA3MDM2 | |
| SCHEMBL4941048 | 0.76 | SLC9A1 (0.69) | SLC9A1ALDH1A1HPGDS1PR4S1PR2 | |
| SCHEMBL27649078 | 0.75 | SLC9A1 (0.58) | SLC9A1ALDH1A1HPGDADORA3MDM2 | |
| SCHEMBL27649079 | 0.74 | SLC9A1 (0.57) | SLC9A1ALDH1A1HPGDADORA3RORC | |
| SCHEMBL6010133 | 0.74 | SLC9A1 (0.51) | SLC9A1ALDH1A1HPGDTSHRS1PR4 | |
| SCHEMBL2324496 | 0.73 | MAPT (0.46) | ALDH1A1HPGDS1PR4S1PR2S1PR3 | |
| SCHEMBL4943380 | 0.72 | SLC9A1 (1.00) | SLC9A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |