Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009508 | 0.80 | SLC9A1 (0.56) | SLC9A1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL6009523 | 0.79 | ALDH1A1 (0.59) | SLC9A1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6010447 | 0.76 | ALDH1A1 (0.52) | SLC9A1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2321499 | 0.74 | SLC9A1 (0.45) | SLC9A1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4943006 | 0.74 | SLC9A1 (0.67) | SLC9A1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3632568 | 0.72 | IRAK4 (0.50) | SLC9A1ALDH1A1HSD17B10IRAK4MAPT | |
| SCHEMBL31634047 | 0.72 | IRAK4 (0.50) | SLC9A1ALDH1A1HSD17B10IRAK4MAPT | |
| SCHEMBL6010130 | 0.70 | ALDH1A1 (0.53) | SLC9A1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4946454 | 0.69 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL1465246 | 0.68 | IRAK4 (0.47) | ALDH1A1KDM4ETDP1IRAK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |