Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275196 | 0.90 | TSHR (0.41) | ALDH1A1TSHRLMNATHRBCYP2D6 | |
| SCHEMBL19898984 | 0.85 | TSHR (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL29754447 | 0.82 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL31384482 | 0.81 | LMNA (0.32) | LMNA | |
| SCHEMBL13468872 | 0.81 | TSHR (0.42) | ALDH1A1TSHRTHRB | |
| SCHEMBL501593 | 0.81 | LMNA (0.40) | ALDH1A1TSHRLMNATHRB | |
| SCHEMBL4566106 | 0.81 | TSHR (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL28865022 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL22231348 | 0.80 | TSHR (0.42) | ALDH1A1TSHRTHRB | |
| SCHEMBL9481348 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229423-A1 | Process for the production of monodisperse and narrow disperse monofunctional silicones | JOHNSON & JOHNSON VISION CARE, INC. | 2006-10-12 | — | — | US | disclosed |
| US-5409731-A | Method for imparting a hydrophilic nature to a contact lens | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1995-04-25 | — | — | US | disclosed |
| US-4235985-A | ORGANOSILOXANE-CONTAINING POLYMETHACRYLATE | TOYO CONTACT LENS CO., LTD. (JP) | 1980-11-25 | — | — | US | disclosed |