Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009501 | 0.85 | ALDH1A1 (0.62) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6009509 | 0.81 | SLC9A1 (0.56) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6009527 | 0.80 | ALDH1A1 (0.59) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6009556 | 0.78 | SLC9A1 (0.56) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL27330465 | 0.77 | KDM4E (0.58) | HPGDALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL4946224 | 0.76 | SLC9A1 (0.69) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL4697667 | 0.76 | HPGD (0.65) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL6010140 | 0.74 | PIK3CA (0.57) | SLC9A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL3030714 | 0.74 | ALDH1A1 (0.50) | HPGDALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL1728691 | 0.73 | MAPT (0.64) | HPGDALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |