Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130032 | 0.88 | KMT2A (0.61) | EPHX2CA12CA1CA2CA5A | |
| SCHEMBL6584405 | 0.87 | CFD (0.65) | SIRT2EPHX2KMT2AMEN1MAPK8 | |
| SCHEMBL8748442 | 0.87 | KMT2A (0.60) | EPHX2CA12CA1CA2CA5A | |
| SCHEMBL9525046 | 0.82 | EPHX2 (0.60) | EPHX2CA12CA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL9626414 | 0.81 | EPHX2 (0.58) | EPHX2CA12CA1CA2CA5A | |
| SCHEMBL5497587 | 0.79 | CYP1A1 (0.57) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1129693 | 0.79 | KDM4C (0.61) | EPHX2CA12CA1CA2CA5A | |
| SCHEMBL6580500 | 0.77 | EPHX2 (0.57) | EPHX2CA12CA1CA2CA5A | |
| SCHEMBL11900270 | 0.76 | EPHX2 (0.81) | SIRT2EPHX2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5496472 | 0.76 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696898-A2 | ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005055928-A2 | ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-06-23 | — | — | WO | disclosed |