Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 6/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | PLAT | P00750 | 4/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731103 | 0.84 | PLAU (0.58) | DEGS1PLAUMEN1NPC1RAB9A | |
| SCHEMBL1707304 | 0.81 | GFER (0.64) | F12DEGS1PLAUMEN1NPC1 | |
| SCHEMBL11880294 | 0.81 | GFER (0.61) | DEGS1MEN1KMT2AMPOCYP3A4 | |
| Hydrochloric Acid SCHEMBL5693969 | 0.80 | GFER (0.62) | F12DEGS1PLAUMEN1NPC1 | |
| SCHEMBL14880024 | 0.79 | KDM4E (0.60) | F12DEGS1MEN1NPC1RAB9A | |
| SCHEMBL28707902 | 0.79 | LCK (0.70) | F12PLAUMEN1NPC1RAB9A | |
| SCHEMBL1808865 | 0.79 | LCK (0.70) | F12PLAUMEN1NPC1RAB9A | |
| SCHEMBL5434715 | 0.78 | SCN2A (0.50) | F12DEGS1PLAUMEN1NPC1 | |
| Terephthalamide SCHEMBL28563305 | 0.77 | PARP10 (0.61) | F12PLAUMEN1NPC1RAB9A | |
| SCHEMBL20704988 | 0.76 | PLAU (0.57) | F12DEGS1PLAUMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100400506-C | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2008-07-09 | — | — | CN | claimed |
| US-7030261-B2 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-04-18 | — | — | US | claimed |
| CN-1680302-A | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-10-12 | — | — | CN | claimed |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2005-09-01 | — | — | US | claimed |
| EP-1564206-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-08-17 | — | — | EP | claimed |
| CN-100400506-C | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2008-07-09 | — | — | CN | disclosed |
| CN-100400506-C | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2008-07-09 | — | — | CN | disclosed |
| CN-100400506-C | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2008-07-09 | — | — | CN | disclosed |
| US-7030261-B2 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-04-18 | — | — | US | disclosed |
| US-7030261-B2 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-04-18 | — | — | US | disclosed |
| US-7030261-B2 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-04-18 | — | — | US | disclosed |
| CN-1680302-A | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1680302-A | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1680302-A | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2005-10-12 | — | — | CN | disclosed |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2005-09-01 | — | — | US | disclosed |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2005-09-01 | — | — | US | disclosed |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2005-09-01 | — | — | US | disclosed |
| EP-1564206-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-1564206-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-1564206-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | HPD, UGDH, HAAO | F12 4333/4885DEGS1 3889/4885PLAU 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.