SCHEMBL6010171

SCHEMBL6010171

CC(=O)Nc1ccccc1C(=O)OC1(C)CCCCC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.46
POLB P06746 1/20 0.46
KDM4E B2RXH2 8/20 0.45
ALDH1A1 P00352 7/20 0.45
LMNA P02545 3/20 0.45
HPGD P15428 4/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
CYP2C9 P11712 1/20 0.43
RAB9A P51151 3/20 0.43
GAA P10253 1/20 0.43
STAT1 P42224 1/20 0.43
HSD17B10 Q99714 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALOX12 P18054 1/20 0.42
NPC1 O15118 2/20 0.42
KMT2A Q03164 1/20 0.41
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11124200 0.84 SCN1A (0.43) CYP2C19KDM4EALDH1A1LMNANPSR1
Cinnamic Acid SCHEMBL9102732 0.80 MAPT (0.37) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL578103 0.79 LMNA (0.49) CYP2C19KDM4EALDH1A1LMNAHPGD
SCHEMBL27980151 0.78 ALDH1A1 (0.50) POLBKDM4EALDH1A1HPGDMAPT
SCHEMBL1640485 0.73 KMT2A (0.71) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL29655205 0.73 KMT2A (0.71) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL15114720 0.72 KDM4E (0.66) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL1479151 0.68 ALDH1A1 (0.67) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL29572294 0.68 ALDH1A1 (0.67) CYP2C19POLBKDM4EALDH1A1LMNA
SCHEMBL14544619 0.68 CYP2C19 (0.56) CYP2C19POLBKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
EP-0713383-B1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1998-06-17 EP claimed
EP-0557089-B1 Sunscreen agents containing layered double hydroxides UNILEVER PLC (GB) 1996-05-29 EP claimed
US-5474762-A Ultraviolet absorber having a metal complexes of double hydroxide; water insolubility, nondiffusing CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1995-12-12 US claimed
EP-0557089-A1 Sunscreen agents containing layered double hydroxides UNILEVER PLC (GB) 1993-08-25 EP claimed
CN-115348867-B Topically applicable lysate (Ly) of plant guayule dedifferentiated cells for eliminating or reducing skin inflammation 化工产品开发公司SEPPIC 2024-05-17 CN disclosed
CN-112074326-B Composition based on caffeoylquinic acid, cosmetic use and cosmetic composition comprising same 化工产品开发公司SEPPIC 2024-03-08 CN disclosed
CN-117479921-A Copolymer thickening composition for thickening polar or non-polar oils comprising at least one oil and at least one poly (itaconate) 化工产品开发公司SEPPIC 2024-01-30 CN disclosed
CN-117479922-A Thickening composition for thickening polar or nonpolar oils 化工产品开发公司SEPPIC 2024-01-30 CN disclosed
CN-117222690-A Polymer in the form of a powdery solid and having the property of thickening polar medium 化工产品开发公司SEPPIC 2023-12-12 CN disclosed
CN-111511714-B Novel compositions of fatty amino acids and diols, process for preparing same, and cosmetic or pharmaceutical compositions produced therefrom 化工产品开发公司SEPPIC 2023-11-28 CN disclosed
CN-110461299-B Method for improving the organoleptic properties of an oil-in-water emulsion 化工产品开发公司SEPPIC 2023-09-15 CN disclosed
WO-1995005150-A1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1995-02-23 WO disclosed
EP-0557089-A1 Sunscreen agents containing layered double hydroxides UNILEVER PLC (GB) 1993-08-25 EP disclosed
US-4925653-A Sunscreen composition containing polyisobutylene and its use for the protection of human epidermis against ultraviolet radiations L'OREAL (FR) 1990-05-15 US disclosed
US-4804531-A Cosmetic screening composition containing a UV screen in combination with a polymer obtained by block polymerization in emulsion and its use for the protection of the human epidermis against ultraviolet radiations L'OREAL (FR) 1989-02-14 US disclosed
US-4668505-A Sunscreen method containing polyisobutylene for the protection of human epidermis against ultraviolet radiations L'OREAL (FR) 1987-05-26 US disclosed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0005182-B1 COMPOSITION AGAINST THE ACTION OF LIGHT BAYER AG (DE) 1981-07-29 EP disclosed
EP-0005182-A1 Composition against the action of light BAYER AG (DE) 1979-11-14 EP disclosed