Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321863 | 0.80 | ESR1 (0.44) | SLC9A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6010187 | 0.74 | SLC9A1 (0.50) | SLC9A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL2350940 | 0.73 | ALDH1A1 (0.51) | MEN1ALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL2318469 | 0.72 | ALDH1A1 (0.44) | MEN1ALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL2365421 | 0.71 | IDH1 (0.41) | ALDH1A1HPGDKDM4E | |
| SCHEMBL2319075 | 0.71 | KDM4E (0.37) | ALDH1A1NISCHTDP1KDM4EMAPT | |
| SCHEMBL4942913 | 0.71 | SLC9A1 (0.64) | SLC9A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL2324206 | 0.70 | SLC9A1 (0.48) | SLC9A1ALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL2322765 | 0.70 | SLC9A1 (0.48) | SLC9A1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL13830012 | 0.70 | NISCH (0.52) | SLC9A1HPGDNISCHL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |