Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338402 | 0.81 | ESR1 (0.63) | ESR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6010182 | 0.80 | SLC9A1 (0.50) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2323850 | 0.79 | ALOX5 (0.43) | SLC9A1 | |
| SCHEMBL2321499 | 0.79 | SLC9A1 (0.45) | ESR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2350940 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2318469 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2324206 | 0.72 | SLC9A1 (0.48) | ALDH1A1HPGDKMT2AMAPTGAA | |
| SCHEMBL2321869 | 0.72 | KDM4E (0.47) | ESR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2324496 | 0.69 | MAPT (0.46) | ESR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11865671 | 0.68 | CA1 (0.45) | ESR1ALDH1A1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |