SCHEMBL6010256

SCHEMBL6010256

O=C(O)C(Cc1ccc(O)cc1)N(C(=O)C(O)CO)C(=O)C(O)CO

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.46
TRPV1 Q8NER1 1/20 0.40
MME P08473 3/20 0.40
ACE P12821 2/20 0.40
POLB P06746 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
KDM6B O15054 1/20 0.37
CA2 P00918 1/20 0.37
CAMK2A Q9UQM7 1/20 0.37
FOLH1 Q04609 1/20 0.37
NAALAD2 Q9Y3Q0 1/20 0.37
CYP2D6 P10635 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009849 0.88 CYP1A2 (0.46) SLC7A5MMEFOLH1
SCHEMBL9754096 0.80 SLC7A5 (0.55) SLC7A5POLBESR1ESR2CA2
SCHEMBL7163413 0.79 SLC7A5 (0.58) SLC7A5MMEACEPOLBESR1
SCHEMBL7163410 0.79 SLC7A5 (0.58) SLC7A5MMEACEPOLBESR1
SCHEMBL16275179 0.79 SLC7A5 (0.54) SLC7A5MMEACEESR1ESR2
SCHEMBL16275180 0.79 SLC7A5 (0.54) SLC7A5MMEACEESR1ESR2
SCHEMBL8665221 0.77 SLC7A5 (0.59) SLC7A5TRPV1
SCHEMBL8712794 0.77 SLC7A5 (0.59) SLC7A5TRPV1
SCHEMBL6010285 0.76 SLC7A5 (0.46) SLC7A5TRPV1MMEACEPOLB
SCHEMBL6010271 0.76 SLC7A5 (0.46) SLC7A5TRPV1MMEACEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA SLC7A5 1780/4885TRPV1 786/4885MME 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.