Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010531 | 0.85 | UGT1A1 (0.43) | CTSSCTSKCTSBCTSLCNR1 | |
| SCHEMBL6010283 | 0.85 | UGT1A1 (0.43) | CTSSCTSKCTSBCTSLCNR1 | |
| SCHEMBL2434947 | 0.84 | CTSS (0.48) | CTSSCTSKCTSBCTSLCNR1 | |
| SCHEMBL9378904 | 0.73 | CTSS (0.41) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL6664759 | 0.73 | ATM (0.41) | CTSSCTSKCTSBCTSLCNR1 | |
| SCHEMBL6669325 | 0.73 | ATM (0.41) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL6663482 | 0.73 | KLK5 (0.41) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL6666632 | 0.71 | ALDH1A1 (0.40) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL3804911 | 0.70 | KLK5 (0.54) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL5750531 | 0.69 | CTSS (0.58) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697344-A2 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058841-A2 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 2005-06-30 | — | — | WO | disclosed |