Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832312 | 0.84 | HPGD (0.49) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2320167 | 0.80 | EGFR (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL2324206 | 0.79 | SLC9A1 (0.48) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL13990243 | 0.77 | ALDH1A1 (0.70) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL13078464 | 0.75 | SLC9A1 (0.67) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2549273 | 0.75 | PIK3CG (0.58) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3741650 | 0.75 | SLC9A1 (0.67) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL6669312 | 0.74 | SLC9A1 (0.73) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4939182 | 0.74 | SLC9A1 (0.65) | SLC9A1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2346044 | 0.74 | ALDH1A1 (0.46) | SLC9A1ALDH1A1HPGDSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |