Naphthoquinone

Naphthoquinone

SCHEMBL6010449

O=C1C=CC(=O)c2ccccc21.[N-]=[N+]=N.[N-]=[N+]=[N-].[N-]=[N+]=[N-].[N-]=[N+]=[N-]

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.67
IDO1 P14902 5/20 0.67
MAOA P21397 3/20 0.67
PIN1 Q13526 2/20 0.67
EHMT2 Q96KQ7 2/20 0.67
MAOB P27338 2/20 0.67
SNCA P37840 2/20 0.67
AKT1 P31749 1/20 0.67
MAP2K1 Q02750 1/20 0.67
NSD1 Q96L73 1/20 0.67
EHMT1 Q9H9B1 1/20 0.67
MEN1 O00255 9/20 0.41
KMT2A Q03164 9/20 0.41
ALDH1A1 P00352 8/20 0.41
MAPT P10636 7/20 0.41
HPGD P15428 5/20 0.41
RECQL P46063 4/20 0.41
KDM4E B2RXH2 4/20 0.41
THRB P10828 4/20 0.41
ALOX15 P16050 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoquinone SCHEMBL11132565 1.00 CDC25B (0.67) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL60195 1.00 CDC25B (0.67) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL9704148 1.00 CDC25B (0.67) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL482597 0.98 IDO1 (0.70) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL7526925 0.94 CDC25B (0.58) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL29458764 0.93 IDO1 (0.78) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL482594 0.93 IDO1 (0.78) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL29837141 0.93 IDO1 (0.78) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL1395610 0.90 IDO1 (0.54) CDC25BIDO1MAOAPIN1EHMT2
Naphthoquinone SCHEMBL10579011 0.90 CDC25B (0.54) CDC25BIDO1MAOAPIN1EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1680711-A2 NOVEL PHOTOSENSITIVE RESIN COMPOSITIONS Fujifilm Electronic Materials USA, Inc. (US) 2006-07-19 EP disclosed
WO-2005038524-A3 NOVEL PHOTOSENSITIVE RESIN COMPOSITIONS ARCH SPEC CHEM INC (US) 2006-06-22 WO disclosed
WO-2005038524-A2 NOVEL PHOTOSENSITIVE RESIN COMPOSITIONS ARCH SPECIALTY CHEMICALS, INC. (US) 2005-04-28 WO disclosed