SCHEMBL6010454

SCHEMBL6010454

O=C(O)CC[C@H](NOCC(O)CO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 12/20 0.46
NAALAD2 Q9Y3Q0 2/20 0.46
RIMKLA Q8IXN7 1/20 0.46
GGH Q92820 1/20 0.40
TET2 Q6N021 3/20 0.38
KDM4A O75164 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
TET3 O43151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009547 0.98 FOLH1 (0.44) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL28491840 0.87 KMT2A (0.38) FOLH1NAALAD2RIMKLA
SCHEMBL6009834 0.84 TGFBR1 (0.40)
SCHEMBL6010380 0.81 FOLH1 (0.39) FOLH1
SCHEMBL28008104 0.80 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL28008105 0.80 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHTET2
SCHEMBL6009533 0.80 FOLH1 (0.44) FOLH1
SCHEMBL6010244 0.80 MAPK1 (0.41)
SCHEMBL6009842 0.79 KDM4E (0.40) FOLH1
Hydrochloric Acid SCHEMBL6010128 0.78 FOLH1 (0.43) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA FOLH1 1267/4885NAALAD2 114/4885RIMKLA 1373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.