Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL370134 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL27278828 | 0.95 | KDM4E (0.50) | — | |
| Hydrochloric Acid SCHEMBL3633233 | 0.90 | — | — | |
| Water SCHEMBL27363166 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL5429216 | 0.90 | — | — | |
| SCHEMBL232317 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL27562909 | 0.86 | — | — | |
| Water SCHEMBL187547 | 0.84 | — | — | |
| SCHEMBL7553746 | 0.84 | — | — | |
| Fluoride Ion SCHEMBL1812697 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053232-B2 | Lewis acid ionic liquids | SACHEM, INC. (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040122229-A1 | Lewis acid ionic liquids | SACHEM, INC. | 2004-06-24 | — | — | US | disclosed |
| WO-2004016571-A2 | LEWIS ACID IONIC LIQUIDS | SACHEM, INC. (US) | 2004-02-26 | — | — | WO | disclosed |