Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GALR2 | O43603 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988172 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11075976 | 0.85 | GPR35 (0.59) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL10877588 | 0.84 | GPR35 (0.55) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL2310798 | 0.84 | TDP1 (0.48) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL2312711 | 0.83 | MAPT (0.54) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL267821 | 0.81 | MAPT (0.65) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL27516180 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL7021997 | 0.81 | GPR35 (0.60) | ALDH1A1LMNAPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL11682561 | 0.79 | AKR1C4 (0.55) | ALDH1A1NPSR1HPGDMAPT | |
| SCHEMBL31563703 | 0.79 | TTR (0.50) | ALDH1A1LMNAPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| CN-1333771-A | Benzoxazole derivative and drug containing the same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2002-01-30 | — | — | CN | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |