Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16391312 | 0.79 | MAOB (0.41) | RAB9ANPC1POLBCASP3SENP7 | |
| SCHEMBL21487058 | 0.72 | NPC1 (0.43) | LMNARAB9ANPC1POLBCASP3 | |
| SCHEMBL6010774 | 0.72 | AHR (0.36) | LMNATHRBPOLBHSD17B10ALDH1A1 | |
| SCHEMBL6010882 | 0.72 | ESR1 (0.39) | KMT2AMEN1 | |
| SCHEMBL6010815 | 0.70 | CHRNB2 (0.39) | — | |
| SCHEMBL9101380 | 0.70 | FBP1 (0.33) | — | |
| SCHEMBL16391300 | 0.69 | MAOB (0.36) | LMNATHRBCYP1A2MAOAALOX15 | |
| SCHEMBL16391287 | 0.69 | GABRA1 (0.40) | — | |
| SCHEMBL6010848 | 0.69 | ESR1 (0.39) | THRBPGK1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL16391333 | 0.67 | ESR1 (0.42) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |