Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 8/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010815 | 0.86 | CHRNB2 (0.39) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| SCHEMBL6010899 | 0.83 | CHRNB2 (0.37) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| Hydrochloric Acid SCHEMBL6010829 | 0.83 | CHRNB2 (0.37) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| SCHEMBL6010809 | 0.81 | F10 (0.44) | HTR6F10IRAK4 | |
| Hydrochloric Acid SCHEMBL6010656 | 0.80 | F10 (0.43) | HTR6F10IRAK4 | |
| SCHEMBL6010862 | 0.79 | HTR6 (0.40) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| SCHEMBL6010844 | 0.79 | CHRNB2 (0.38) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| Hydrochloric Acid SCHEMBL6010978 | 0.79 | HTR6 (0.39) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| SCHEMBL6010864 | 0.76 | CHRNB2 (0.43) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 | |
| SCHEMBL6010788 | 0.76 | HTR6 (0.41) | CHRNA1CHRNB2CHRNA7CHRNA4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |