Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 8/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6010829 | 0.99 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNA1CHRNA7KDM4E | |
| SCHEMBL6010815 | 0.89 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA1CHRNA7F10 | |
| SCHEMBL6010862 | 0.84 | HTR6 (0.40) | CHRNB2CHRNA4CHRNA1CHRNA7HTR6 | |
| SCHEMBL6010871 | 0.83 | ACACB (0.37) | CHRNB2CHRNA4CHRNA1CHRNA7F10 | |
| SCHEMBL6010809 | 0.83 | F10 (0.44) | KDM4EF10IRAK4HTR6 | |
| Hydrochloric Acid SCHEMBL6010978 | 0.83 | HTR6 (0.39) | CHRNB2CHRNA4CHRNA1CHRNA7HTR6 | |
| Hydrochloric Acid SCHEMBL6010656 | 0.83 | F10 (0.43) | KDM4EF10IRAK4HTR6 | |
| SCHEMBL6010844 | 0.81 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNA1CHRNA7HTR6 | |
| SCHEMBL6010864 | 0.81 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNA1CHRNA7HTR6 | |
| SCHEMBL6010788 | 0.78 | HTR6 (0.41) | CHRNB2CHRNA4CHRNA1CHRNA7F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |