Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011981 | 0.90 | LMNA (0.46) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10811553 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3964955 | 0.87 | LMNA (0.48) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL28631050 | 0.87 | ALDH1A1 (0.46) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3972497 | 0.87 | LMNA (0.48) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL10732616 | 0.85 | LMNA (0.52) | LMNATSHROPRM1SPHK1ADH1B | |
| SCHEMBL28082913 | 0.85 | ALDH1A1 (0.52) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL4557001 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL3438481 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL9033403 | 0.84 | LMNA (0.56) | LMNAALDH1A1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622879-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099160-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-18 | — | — | WO | disclosed |