SCHEMBL6011981

SCHEMBL6011981

CCCC(CCC)CCCCCCCCC(C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
OPRM1 P35372 1/20 0.36
SPHK1 Q9NYA1 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
PLA2G1B P04054 1/20 0.32
PLA2G2A P14555 1/20 0.32
TSHR P16473 2/20 0.32
CYP3A4 P08684 1/20 0.32
DNM1 Q05193 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10732616 0.95 LMNA (0.52) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL28647647 0.93 LMNA (0.50) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL28901552 0.93 LMNA (0.50) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL5594937 0.92 LMNA (0.43) LMNAOPRM1ALDH1A1TDP1TSHR
SCHEMBL18432779 0.90 LMNA (0.48) LMNAOPRM1SPHK1ALDH1A1TDP1
SCHEMBL6011899 0.90 LMNA (0.42) LMNAOPRM1SPHK1ALDH1A1TDP1
SCHEMBL7709532 0.89 LMNA (0.56) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL28747885 0.89 LMNA (0.56) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL30598355 0.89 LMNA (0.56) LMNAOPRM1SPHK1ADH1BADH1C
SCHEMBL30598358 0.89 LMNA (0.56) LMNAOPRM1SPHK1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622879-A1 PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME Sumitomo Chemical Company, Limited (JP) 2006-02-08 EP disclosed
WO-2004099160-A1 PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-18 WO disclosed