Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011905 | 0.70 | PTGS1 (0.36) | ARSHBGPTGS1LMNAMAPT | |
| SCHEMBL6011908 | 0.68 | SHBG (0.71) | ARSHBGPGR | |
| SCHEMBL3452000 | 0.67 | SHBG (0.49) | ARSHBGPGR | |
| SCHEMBL3875240 | 0.67 | SHBG (0.65) | ARSHBGPGRLMNA | |
| SCHEMBL3875239 | 0.67 | SHBG (0.65) | ARSHBGPGRLMNA | |
| SCHEMBL3453517 | 0.64 | AR (0.50) | ARSHBGPGRLMNAMAPT | |
| SCHEMBL24102415 | 0.64 | AR (0.82) | ARPGRLMNAMAPT | |
| SCHEMBL5334484 | 0.63 | AR (0.45) | ARSHBGPGRLMNAMAPT | |
| SCHEMBL24102572 | 0.62 | AR (0.79) | ARPGRLMNAMAPT | |
| SCHEMBL24102820 | 0.60 | AR (0.65) | ARSHBGPGRPTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379253-B1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | US GOV HEALTH & HUMAN SERV (US) | 2006-03-29 | — | — | EP | claimed |