Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011919 | 0.81 | MYC (0.42) | MYCHDAC8TP53MAPTLMNA | |
| SCHEMBL6011820 | 0.81 | MYC (0.33) | MYCHDAC8TP53MAPTLMNA | |
| SCHEMBL4591126 | 0.81 | MYC (0.42) | MYCHDAC8TP53MAPTLMNA | |
| SCHEMBL5409716 | 0.74 | KDM4E (0.37) | MYCHDAC8MAPTIDO1 | |
| SCHEMBL6012068 | 0.73 | PDE4D (0.43) | MAPT | |
| SCHEMBL6012030 | 0.73 | MYC (0.34) | MYCHDAC8TP53MAPTLMNA | |
| SCHEMBL6011791 | 0.71 | TAS2R8 (0.35) | MAPT | |
| SCHEMBL23030047 | 0.67 | HDAC8 (0.47) | HDAC8TP53MAPTLMNA | |
| Hydrochloric Acid SCHEMBL17371704 | 0.67 | HDAC8 (0.49) | HDAC8TP53MAPTLMNA | |
| SCHEMBL1516345 | 0.65 | LMNA (0.47) | HDAC8MAPTLMNASLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682549-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | Sepracor Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044818-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR, INC. (US) | 2005-05-19 | — | — | WO | disclosed |