Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591126 | 0.79 | MYC (0.42) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6012067 | 0.77 | PDE4D (0.41) | PDE4DRAB9AMAPTP2RX7NPSR1 | |
| SCHEMBL6011820 | 0.73 | MYC (0.33) | MAPTHPGDALDH1A1 | |
| SCHEMBL6012048 | 0.73 | MYC (0.33) | MAPT | |
| SCHEMBL5409716 | 0.71 | KDM4E (0.37) | MAPTP2RX7NPSR1HPGDALDH1A1 | |
| SCHEMBL6012030 | 0.69 | MYC (0.34) | MAPTNPSR1ALDH1A1 | |
| SCHEMBL6011791 | 0.68 | TAS2R8 (0.35) | MAPT | |
| SCHEMBL6012071 | 0.66 | NR1H4 (0.45) | PDE4DRAB9AMAPTP2RX7NPSR1 | |
| Hydrochloric Acid SCHEMBL17371704 | 0.66 | HDAC8 (0.49) | MAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28524227 | 0.65 | RAB9A (0.64) | PDE4DRAB9AMAPTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682549-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | Sepracor Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044818-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR, INC. (US) | 2005-05-19 | — | — | WO | disclosed |