Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012059 | 0.80 | TGFBR1 (0.47) | TGFBR1 | |
| SCHEMBL6012097 | 0.78 | TGFBR1 (0.40) | TGFBR1 | |
| SCHEMBL6012068 | 0.77 | PDE4D (0.43) | PDE4DP2RX7RAB9AMAPTNPSR1 | |
| SCHEMBL6012047 | 0.76 | TGFBR1 (0.41) | TGFBR1 | |
| SCHEMBL6011819 | 0.75 | TGFBR1 (0.40) | TGFBR1 | |
| SCHEMBL6012051 | 0.74 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL5409710 | 0.72 | TGFBR1 (0.41) | TGFBR1MAPTNPSR1TSHR | |
| SCHEMBL6012071 | 0.70 | NR1H4 (0.45) | PDE4DP2RX7RAB9AMAPTNPSR1 | |
| SCHEMBL6011787 | 0.70 | TGFBR1 (0.38) | TGFBR1 | |
| SCHEMBL2938107 | 0.67 | GABRB2 (0.55) | PDE4DRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682549-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | Sepracor Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044818-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR, INC. (US) | 2005-05-19 | — | — | WO | disclosed |