Phosphoric Acid

SCHEMBL6012155

O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])([O-])c1ccccc1S(=O)(=O)O.O=P([O-])([O-])c1ccccc1S(=O)(=O)O.O=P([O-])([O-])c1ccccc1S(=O)(=O)O.O=P([O-])([O-])c1ccccc1S(=O)(=O)O.[Zr+4].[Zr+4].[Zr+4]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	MYC	P01106	1/20	0.36

▸	TSHR	P16473	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	TTR	P02766	2/20	0.34

▸	FABP4	P15090	1/20	0.32

▸	CCNA2	P20248	1/20	0.32

▸	CDK2	P24941	1/20	0.32

▸	MAPK14	Q16539	1/20	0.32

▸	POLB	P06746	1/20	0.32

▸	CYP2D6	P10635	1/20	0.32

▸	NR4A1	P22736	1/20	0.31

▸	CYP1A2	P05177	1/20	0.30

▸	CA2	P00918	1/20	0.30

▸	CA4	P22748	1/20	0.30

▸	CA5A	P35218	1/20	0.30

▸	SNCA	P37840	1/20	0.30

▸	PGAM1	P18669	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL6012157	0.96	MYC (0.36)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL4251055	0.96	MYC (0.38)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL8842465	0.89	MYC (0.34)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL8842457	0.89	MYC (0.34)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL340555	0.80	PTK2B (0.40)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL1594135	0.80	TTR (0.37)	MYCTTRFABP4CCNA2CDK2
Phosphoric Acid SCHEMBL1593306	0.79	TTR (0.36)	MYCTTRFABP4CCNA2CDK2
SCHEMBL9943663	0.79	PTK2B (0.39)	MYCTSHRSMN1; SMN2TTRFABP4
SCHEMBL10781743	0.78	MYC (0.41)	MYCTSHRSMN1; SMN2TTRFABP4
Phosphoric Acid SCHEMBL6012154	0.77	PTK2B (0.38)	MYCTSHRSMN1; SMN2TTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1205994-B1	MEMBRANE-ELECTRODE ASSEMBLY FOR POLYMERIC MEMBRANE FUEL CELLS	NUVERA FUEL CELLS LLC (US)	2018-01-10	—	—	EP	disclosed
US-7144652-B2	Membrane-electrode assembly for polymeric membrane fuel cell	Nuvera Fuel Cells Europe S.r.l. de Nora Electrodi S.p.A. (IT)	2006-12-05	—	—	US	disclosed
US-20020058173-A1	Membrane-electrode assembly for polymeric membrane fuel cell	BANK OF AMERICA, N.A. (A NATIONAL BANKING INSTITUTION)	2002-05-16	—	—	US	disclosed
EP-1205994-A2	Membrane-electrode assembly for polymeric membrane fuel cells	Nuvera Fuel Cells Europe S.R.L. (IT)	2002-05-15	—	—	EP	disclosed
US-5616749-A	REACTING PHENYLPHOSPHONIC ACID WITH FUMING SULFURIC ACID TO FORM SULFOPHENYLPHOSPHONIC ACID, COOLING, MIXING WITH PHOSPHORUS ACID, A ZIRCONIUM SALT AND PHENYL PHOSPHONIC ACID STIRRING, HEATING, CO-PRECIPITATING, WASHING AND DRYING	NATIONAL SCIENCE COUNCIL (TW)	1997-04-01	—	—	US	disclosed