Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CHAT | P28329 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943663 | 0.98 | PTK2B (0.39) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL340555 | 0.96 | PTK2B (0.40) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL8842454 | 0.92 | PTK2B (0.36) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL9517530 | 0.82 | PTK2B (0.39) | PTK2BPOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL10781743 | 0.81 | MYC (0.41) | POLBMYCALDH1A1CA2CA4 | |
| Phosphoric Acid SCHEMBL5534159 | 0.81 | TTR (0.38) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL9453279 | 0.80 | TTR (0.40) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL1727539 | 0.78 | TTR (0.39) | PTK2BPOLBNPC1MYCALDH1A1 | |
| SCHEMBL28093880 | 0.78 | CA2 (0.48) | PTK2BPOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL27661383 | 0.78 | BCAT2 (0.43) | PTK2BPOLBNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205994-B1 | MEMBRANE-ELECTRODE ASSEMBLY FOR POLYMERIC MEMBRANE FUEL CELLS | NUVERA FUEL CELLS LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-7144652-B2 | Membrane-electrode assembly for polymeric membrane fuel cell | Nuvera Fuel Cells Europe S.r.l. de Nora Electrodi S.p.A. (IT) | 2006-12-05 | — | — | US | disclosed |
| US-20020058173-A1 | Membrane-electrode assembly for polymeric membrane fuel cell | BANK OF AMERICA, N.A. (A NATIONAL BANKING INSTITUTION) | 2002-05-16 | — | — | US | disclosed |
| EP-1205994-A2 | Membrane-electrode assembly for polymeric membrane fuel cells | Nuvera Fuel Cells Europe S.R.L. (IT) | 2002-05-15 | — | — | EP | disclosed |
| US-5616749-A | REACTING PHENYLPHOSPHONIC ACID WITH FUMING SULFURIC ACID TO FORM SULFOPHENYLPHOSPHONIC ACID, COOLING, MIXING WITH PHOSPHORUS ACID, A ZIRCONIUM SALT AND PHENYL PHOSPHONIC ACID STIRRING, HEATING, CO-PRECIPITATING, WASHING AND DRYING | NATIONAL SCIENCE COUNCIL (TW) | 1997-04-01 | — | — | US | disclosed |