Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712349 | 0.79 | SIGMAR1 (0.54) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL27678060 | 0.77 | SIGMAR1 (0.51) | SIGMAR1NAMPTUSP2ALDH1A1TSHR | |
| SCHEMBL17888329 | 0.76 | NAMPT (0.59) | NAMPTALDH1A1GABRDGABRA1GABRB1 | |
| SCHEMBL27696613 | 0.75 | SIGMAR1 (0.50) | SIGMAR1NAMPTUSP2ALDH1A1TSHR | |
| SCHEMBL31132974 | 0.75 | NAMPT (0.45) | SIGMAR1NAMPTTSHR | |
| SCHEMBL31132790 | 0.73 | KMT2A (0.41) | NAMPTALDH1A1 | |
| SCHEMBL19226390 | 0.73 | NAMPT (0.56) | NAMPTALDH1A1GABRDGABRA1GABRB1 | |
| SCHEMBL21078090 | 0.73 | NAMPT (0.56) | NAMPTGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL17886798 | 0.73 | NAMPT (0.56) | NAMPTALDH1A1 | |
| SCHEMBL31413271 | 0.72 | KDM4E (0.52) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119091-B2 | Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |