Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413212 | 0.82 | PARP1 (0.63) | — | |
| Trifluoroacetic Acid SCHEMBL16149784 | 0.74 | ATR (0.58) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL16150341 | 0.74 | FASN (0.63) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL16619621 | 0.74 | HTR2B (0.60) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL16620370 | 0.74 | HPGD (0.60) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL6012279 | 0.72 | SIGMAR1 (0.55) | ALDH1A1HSD17B10 | |
| SCHEMBL29744226 | 0.71 | HRH4 (0.62) | KDM4EHPGDSMN1; SMN2HSD17B10POLB | |
| SCHEMBL1664216 | 0.71 | KDM4E (0.97) | KDM4EALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL31413286 | 0.70 | PARP1 (0.63) | — | |
| SCHEMBL3663760 | 0.70 | KDM4E (0.73) | KDM4EALDH1A1HPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042769-A1 | COMPOUNDS AND METHODS FOR INHIBITING POLY(ADP-RIBOSE) POLYMERASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2025-02-27 | — | — | WO | claimed |