Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523367 | 0.76 | SOS1 (0.45) | SOS1SOS2TSHR | |
| SCHEMBL29984958 | 0.76 | POLB (0.40) | SOS1SOS2 | |
| SCHEMBL7449892 | 0.75 | SOS1 (0.35) | SOS1SOS2TSHR | |
| SCHEMBL21538558 | 0.75 | TSHR (0.42) | SOS1SOS2TSHR | |
| SCHEMBL17624763 | 0.74 | SOS1 (0.40) | SOS1SOS2TSHR | |
| SCHEMBL6012735 | 0.74 | SOS1 (0.76) | SOS1SOS2TSHR | |
| SCHEMBL24745284 | 0.73 | SOS1 (0.42) | SOS1SOS2 | |
| SCHEMBL5245237 | 0.73 | SOS1 (0.34) | SOS1SOS2TSHR | |
| SCHEMBL19362277 | 0.73 | SOS1 (0.34) | SOS1SOS2TSHR | |
| SCHEMBL11722966 | 0.73 | SOS1 (0.34) | SOS1SOS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235864-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-7119091-B2 | Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |