SCHEMBL6013231

SCHEMBL6013231

C=CCc1c(O)c(CC=C)c(CC=C)c(-c2ccc(O)cc2)c1CC=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.44
GABRB2 P47870 3/20 0.44
AKR1B1 P15121 1/20 0.41
SENP1 Q9P0U3 3/20 0.41
ESR1 P03372 3/20 0.37
ESR2 Q92731 2/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 4/20 0.36
POLB P06746 1/20 0.36
ALOX5 P09917 1/20 0.36
GABRB1 P18505 1/20 0.36
RXRA P19793 1/20 0.36
CNR1 P21554 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
CNR2 P34972 1/20 0.36
GABRA2 P47869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197923 0.91 SENP1 (0.39) GABRA1GABRB2AKR1B1SENP1ESR1
SCHEMBL790695 0.76 GABRA1 (0.41) GABRA1GABRB2AKR1B1MEN1MAPT
SCHEMBL21002017 0.75 AKR1B1 (0.44) GABRA1GABRB2AKR1B1ESR1ESR2
SCHEMBL31326920 0.75 GABRA1 (0.47) GABRA1GABRB2AKR1B1ESR1ESR2
SCHEMBL30112817 0.75 GABRA1 (0.51) GABRA1GABRB2AKR1B1ESR1ESR2
SCHEMBL10454695 0.75 SENP1 (0.44) GABRA1GABRB2AKR1B1SENP1ESR1
SCHEMBL1354946 0.74 GABRA1 (0.38) GABRA1GABRB2AKR1B1MEN1MAPT
SCHEMBL6273663 0.73 GABRA1 (0.39) GABRA1GABRB2AKR1B1MEN1MAPT
SCHEMBL6009677 0.72 GABRA1 (0.47) GABRA1GABRB2AKR1B1ESR1ESR2
SCHEMBL11639061 0.71 GABRA1 (0.38) GABRA1GABRB2AKR1B1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730805-A Preparation method of biphenol 锦州三丰科技有限公司 2023-09-12 CN disclosed
CN-108623786-B Oxazolidone ring-containing epoxy resin composition, method for producing same, curable resin composition, and cured product 日铁化学材料株式会社 2022-04-05 CN disclosed
US-20060088748-A1 Novel compositions of monomers, oligomers and polymers and methods for making the same HOKU SCIENTIFIC, INC. - A DELAWARE CORPORATION 2006-04-27 US disclosed
US-20050014975-A1 Process for preparing methylenedianiline and methylenebis (phenylisocyanate) STROFER ECKHARD (DE) 2005-01-20 US disclosed
US-6831192-B2 Process for preparing methylenedianiline and methylenebis(phenyl isocyanate) BASF AKTIENGESELLSCHAFT (DE) 2004-12-14 US disclosed
US-6576788-B1 METHOD FOR PRODUCING MIXTURES CONSISTING OF DIPHENYLMETHANE DIISOCYANATES AND POLYPHENYLENE-POLYMETHYLENE-POLYISOCYANATES CONTAINING A REDUCED AMOUNT OF CHLORINATED SECONDARY PRODUCTS AND WITH A REDUCED IODINE COLOR INDEX BASF AKTIENGESELLSCHAFT (DE) 2003-06-10 US disclosed
US-6433219-B1 REACTING ANILINE WITH FORMALDEHYDE IN PRESENCE OF ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 2002-08-13 US disclosed