Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273663 | 0.97 | GABRA1 (0.39) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL11639061 | 0.94 | GABRA1 (0.38) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL31330939 | 0.93 | GABRA1 (0.41) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL7057557 | 0.89 | GABRA1 (0.35) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL5810793 | 0.83 | KDM4E (0.39) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL22139408 | 0.81 | XDH (0.45) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL5178926 | 0.79 | GABRA1 (0.47) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL5831274 | 0.78 | ALDH1A1 (0.33) | GABRA1GABRB2XDHKDM4EGAA | |
| SCHEMBL5844884 | 0.78 | PTGES (0.36) | KDM4EGAAGLAALDH1A1MEN1 | |
| SCHEMBL5919653 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2XDHKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364946-A | Process for the preparation of substituted pentaalkylchromenes | LONZA LTD. (CH) | 1994-11-15 | — | — | US | claimed |
| EP-0543345-B1 | Substituted pentaalkylchromanes | LONZA AG (CH) | 1994-09-07 | — | — | EP | claimed |
| EP-0543346-B1 | Method for the preparation of substituted pentaalkylchromenes | LONZA AG (CH) | 1994-09-07 | — | — | EP | claimed |
| US-5313007-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-17 | — | — | US | claimed |
| US-5310953-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-10 | — | — | US | claimed |
| JP-6065229-A | — | — | None | — | — | JP | disclosed |
| JP-6080658-A | — | — | None | — | — | JP | disclosed |
| US-20120071692-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AMINES | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| US-7767855-B2 | Method for the continuous production of an amine | BASF SE (DE) | 2010-08-03 | — | — | US | disclosed |
| US-20080200726-A1 | Method For the Continuous Production of an Amine | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-5364946-A | Process for the preparation of substituted pentaalkylchromenes | LONZA LTD. (CH) | 1994-11-15 | — | — | US | disclosed |
| US-5313007-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-17 | — | — | US | disclosed |
| US-5313007-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-17 | — | — | US | disclosed |
| US-5310953-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-10 | — | — | US | disclosed |
| US-5310953-A | Substituted pentaalkylchromans | LONZA LTD. (CH) | 1994-05-10 | — | — | US | disclosed |
| US-5304663-A | Tetraalkyl-substituted 1,4-benzoquinones as intermediates for tetra- or penta-alkyl substituted 6-hydroxy-chromenes | LONZA LTD. (CH) | 1994-04-19 | — | — | US | disclosed |
| JP-H0680658-A | PREPARATION OF SUBSTITUTED PENTAALKYLCHROMEN | LONZA AG | 1994-03-22 | — | — | JP | disclosed |
| JP-H0665229-A | PRODUCTION OF SUBSTITUTED PENTAALKYLCHROMAN | LONZA AG | 1994-03-08 | — | — | JP | disclosed |
| EP-0543346-A1 | Method for the preparation of substituted pentaalkylchromenes | LONZA AG (CH) | 1993-05-26 | — | — | EP | disclosed |
| EP-0543345-A1 | Substituted pentaalkylchromanes | LONZA AG (CH) | 1993-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071692-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AMINES | ADH1A, ADH5, ADH1C | GABRA1 2183/4885GABRB2 3072/4885XDH 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.