Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382916 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL16190003 | 0.80 | — | — | |
| SCHEMBL8348053 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL4289914 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL4956385 | 0.72 | OPRM1 (0.49) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL2522078 | 0.72 | OPRM1 (0.47) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL17925986 | 0.72 | — | — | |
| SCHEMBL248285 | 0.71 | — | — | |
| SCHEMBL8552663 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 | |
| SCHEMBL31580458 | 0.70 | OPRM1 (0.42) | SMN1; SMN2OPRM1OPRL1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122678-B2 | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | WARNER-LAMBERT COMPANY (US) | 2006-10-17 | — | — | US | disclosed |