SCHEMBL8552663

SCHEMBL8552663

CC1(C)CNC(=O)CC(C)(C)C1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
HPGD P15428 1/20 0.34
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2C19 P33261 1/20 0.33
CTSK P43235 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
ATAD2 Q6PL18 1/20 0.33
OPRM1 P35372 1/20 0.32
OPRL1 P41146 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248285 0.87
SCHEMBL26338699 0.77 SMN1; SMN2 (0.39) SMN1; SMN2HPGD
SCHEMBL24433892 0.77 SMN1; SMN2 (0.48) SMN1; SMN2HPGDLMNAKDM4ECYP2C19
SCHEMBL14611425 0.77 SMN1; SMN2 (0.39) SMN1; SMN2LMNAKDM4ECYP2C19ALDH1A1
SCHEMBL21557423 0.77 LMNA (0.50) SMN1; SMN2HPGDLMNAKDM4ECYP2C19
SCHEMBL21667646 0.73 CTSK (0.39) SMN1; SMN2LMNAKDM4ECYP2C19CTSK
SCHEMBL24029385 0.73 SMN1; SMN2 (0.44) SMN1; SMN2LMNAKDM4ECYP2C19
SCHEMBL8550073 0.71
SCHEMBL21042654 0.70 SMN1; SMN2 (0.56) SMN1; SMN2LMNAKDM4ECYP2C19CTSK
SCHEMBL6013404 0.70 SMN1; SMN2 (0.45) SMN1; SMN2CYP11B1CYP11B2OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11531150-B2 Photonic crystal structure and anti-forgery color conversion film comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-12-20 US disclosed
US-20200225391-A1 PHOTONIC CRYSTAL STRUCTURE AND ANTI-FORGERY COLOR CONVERSION FILM COMPRISING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2020-07-16 US disclosed
EP-0824523-A1 NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES G.D. Searle & Co. (US) 1998-02-25 EP disclosed
WO-1996035677-A1 NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES G.D. SEARLE & CO. (US) 1996-11-14 WO disclosed