SCHEMBL6013464

SCHEMBL6013464

O=C(CNO)Nc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.59
EPHX2 P34913 2/20 0.59
HDAC4 P56524 3/20 0.56
HDAC1 Q13547 3/20 0.56
HDAC7 Q8WUI4 3/20 0.56
HDAC11 Q96DB2 3/20 0.56
HDAC8 Q9BY41 3/20 0.56
HDAC6 Q9UBN7 3/20 0.56
HDAC9 Q9UKV0 3/20 0.56
HDAC5 Q9UQL6 3/20 0.56
HDAC3 O15379 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC10 Q969S8 2/20 0.56
KDM4E B2RXH2 1/20 0.56
BRD4 O60885 1/20 0.56
NCOR1 O75376 1/20 0.56
NR1I2 O75469 1/20 0.56
EGFR P00533 1/20 0.56
CYP3A4 P08684 1/20 0.56
LTA4H P09960 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9506366 0.98 MAOB (0.58) MAOBEPHX2HDAC4HDAC1HDAC7
SCHEMBL11458040 0.83 L3MBTL1 (0.66) EPHX2HDAC4HDAC1HDAC7HDAC11
SCHEMBL1561387 0.83 MAPT (0.70) EPHX2HDAC4HDAC1HDAC7HDAC11
SCHEMBL14107963 0.82 MAPT (0.58) EPHX2KDM4EMAPTL3MBTL1SMN1; SMN2
SCHEMBL1689206 0.81 EPHX2 (0.68) MAOBEPHX2HDAC4HDAC1HDAC7
SCHEMBL1420885 0.81 MEN1 (0.57) EPHX2HDAC4HDAC1HDAC7HDAC11
Hydrochloric Acid SCHEMBL11858514 0.81 MAPT (0.68) EPHX2HDAC4HDAC1HDAC7HDAC11
SCHEMBL19585161 0.81 MEN1 (0.57) EPHX2HDAC4HDAC1HDAC7HDAC11
SCHEMBL5969586 0.81 CA1 (0.59) EPHX2MAPTL3MBTL1HTTTP53
SCHEMBL3342586 0.79 L3MBTL1 (0.80) EPHX2HDAC4HDAC1HDAC7HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004111241-A1 PENICILLIN ACYLASE STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2004-12-23 WO claimed
EP-1455734-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES Yu, Ruey J., Dr. (US) 2004-09-15 EP claimed
WO-2003045338-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES YU RUEY J (US) 2003-06-05 WO claimed
EP-1019363-A1 PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE DSM N.V. (NL) 2000-07-19 EP claimed
WO-1998013335-A1 PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE DSM N.V. (NL) 1998-04-02 WO claimed
US-5072041-A OPTICALLY ACTIVE N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND THEIR DERIVATIVES STAMICARBON B.V. (NL) 1991-12-10 US claimed
EP-0030846-A2 Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them ELI LILLY AND COMPANY (US) 1981-06-24 EP claimed
CN-116200968-B Preparation method of white core cardboard for cigarettes 武汉虹之彩包装印刷有限公司 2024-08-09 CN disclosed
CN-116043610-B Preparation method of cigarette packaging paper 武汉虹之彩包装印刷有限公司 2024-05-10 CN disclosed
CN-116200968-A Preparation method of white core cardboard for cigarettes 武汉虹之彩包装印刷有限公司 2023-06-02 CN disclosed
CN-116043610-A Preparation method of cigarette packaging paper 武汉虹之彩包装印刷有限公司 2023-05-02 CN disclosed
CN-109971743-B Penicillin G acylase mutant derived from achromobacter CCM4824 and application thereof 艾美科健株式会社 2022-09-06 CN disclosed
EP-2654665-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2013-10-30 EP disclosed
EP-0012158-A2 Oxime derivatives and their use in the protection of cultivated plants CIBA-GEIGY AG (CH) 1980-06-25 EP disclosed
EP-0010588-A2 Sulfur-containing oxime compounds and their use to protect cultivated plants CIBA-GEIGY AG (CH) 1980-05-14 EP disclosed
EP-0011047-A2 Oxime derivatives to protect cultivated plants CIBA-GEIGY AG (CH) 1980-05-14 EP disclosed
EP-0010143-A2 Oxime derivatives to protect cultivated plants CIBA-GEIGY AG (CH) 1980-04-30 EP disclosed
EP-0010058-A1 Process and compositions for the protection of plant cultures against the phytotoxic action of strong herbicides; oxime ether derivatives CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed
US-4152137-A PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed
US-4070389-A HERBICIDE ANTIDOTES CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed