Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438205 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL4454349 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL29695353 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL62782 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL29438203 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL9370834 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL4894601 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL126595 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL8541737 | 0.92 | MEN1 (0.48) | NPC1RAB9AMDM4MDM2TRPM8 | |
| SCHEMBL8674776 | 0.91 | NPC1 (0.41) | NPC1RAB9AMDM4MDM2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074743-B1 | Herbicidal composition comprising 4-iodo-2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]benzoic esters | HOECHST SCHERING AGREVO GMBH (DE) | 2006-07-11 | — | — | US | disclosed |
| EP-0946100-B1 | HERBICIDES CONTAINING N-[(4,6-DIMETHOXYPYRIMIDINE-2-YL)AMINOCARBONYL]-5-METHYLSULPHONAMIDOMETHYL-2-ALKOXYCARBONYLBENZENE SULPHONAMIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-0831707-B1 | HERBICIDES WITH 4-IODO-2-[3-(4-METHOXY-6-METHYL-1,3,5-TRIAZIN-2-YL)UREIDOSULFONYL]-BENZOIC ACID ESTERS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| CN-1239867-A | Herbicidal compositions comprising N- [ (4, 6-dimethoxypyrimidin-2-yl) aminocarbonyl ] -5-methylsulphinylaminomethyl-2-alkoxycarbonylbenzenesulfonamide | HOECHST SCHERING AGREVO GMBH (DE) | 1999-12-29 | — | — | CN | disclosed |
| US-5990047-A | SYNERGISTIC MIXTURE WITH ONE OR MORE HERBICIDES WHICH ACTS SELECTIVELY IN CEREALS AND/OR MAIZE AGAINST: GRASSES; DICOTS; GRASSES AND DICOTS; OR GRASSES AND BROADLEAF WEEDS IN TRANSGENIC CROPS; OR WHICH ACTS NON-SELECTIVELY IN NONCROPS | HOECHST SCHERING AGREVO GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| EP-0831707-A1 | HERBICIDES WITH 4-IODO-2-[3-(4-METHOXY-6-METHYL-1,3,5-TRIAZIN-2-YL)UREIDOSULFONYL]-BENZOIC ACID ESTERS | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041537-A1 | HERBICIDES WITH 4-IODO-2-[3-(4-METHOXY-6-METHYL-1,3,5-TRIAZIN-2-YL)UREIDOSULFONYL]-BENZOIC ACID ESTERS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-27 | — | — | WO | disclosed |