Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438205 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL6013579 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL29695353 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL62782 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL29438203 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL9370834 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL4894601 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL126595 | 1.00 | NPC1 (0.46) | NPC1RAB9AMDM4MDM2MLYCD | |
| SCHEMBL8541737 | 0.92 | MEN1 (0.48) | NPC1RAB9AMDM4MDM2TRPM8 | |
| SCHEMBL8674776 | 0.91 | NPC1 (0.41) | NPC1RAB9AMDM4MDM2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351571-A2 | SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES | Bayer CropScience AG (DE) | 2003-10-15 | — | — | EP | claimed |
| CN-1407854-A | N-aryi-uracile-based herbicides | BAYER AG (DE) | 2003-04-02 | — | — | CN | claimed |
| CN-1391439-A | Synergistic herbicidal active substance combinations | BAYER AG (DE) | 2003-01-15 | — | — | CN | claimed |
| EP-1221848-A1 | SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-07-17 | — | — | EP | claimed |
| WO-2001035740-A2 | SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-25 | — | — | WO | claimed |
| WO-2001022819-A1 | SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | claimed |
| EP-0613618-B1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID CO (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0407341-B1 | Selective herbicidal agent | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | claimed |
| US-5407897-A | Plant safening agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-18 | — | — | US | claimed |
| EP-0613618-A1 | Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds | AMERICAN CYANAMID COMPANY (US) | 1994-09-07 | — | — | EP | claimed |
| US-5059239-A | Preemergence; postemergence; grains | CIBA-GEIGY CORPORATION (US) | 1991-10-22 | — | — | US | claimed |
| EP-0191736-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | claimed |
| EP-0407341-A1 | Selective herbicidal agent | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | claimed |
| EP-0236273-B1 | SYNERGETIC COMPOSITIONS AND PROCESS FOR SELECTIVE WEED KILLING IN CEREALS | CIBA-GEIGY AG (CH) | 1990-08-08 | — | — | EP | claimed |
| EP-0258184-A2 | Quinoline derivatives as herbicide antagonists for cultivated plants | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | claimed |
| EP-0191736-A2 | Use of quinoline derivatives for the protection of crop plants | CIBA-GEIGY AG (CH) | 1986-08-20 | — | — | EP | claimed |
| US-20170042157-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20140243199-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2014-08-28 | — | — | US | disclosed |
| EP-0258184-A2 | Quinoline derivatives as herbicide antagonists for cultivated plants | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |
| EP-0191736-A2 | Use of quinoline derivatives for the protection of crop plants | CIBA-GEIGY AG (CH) | 1986-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042157-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | GSTM2, GSTM1, CHRM2 | NPC1 3947/4885RAB9A 2680/4885MDM4 1610/4885 |
| US-20140243199-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | SLC16A3, SLC16A7, MTX2 | NPC1 4782/4885RAB9A 4431/4885MDM4 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.